ENHANCED EXTRACTION OF BLOOD AND TISSUE TIME-ACTIVITY CURVES IN CARDIAC MOUSE FDG PET IMAGING BY MEANS OF CONSTRAINED NONNEGATIVE MATRIX FACTORIZATION

We propose an enhanced method to accurately retrieve time-activity curves (TACs) of blood and tissue from dynamic 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) positron emission tomography (PET) cardiac images of mice.The method is noninvasive and consists of using a constrained nonnegative matrix factorization algorithm (CNMF) applied to the matrix (

Taxonomic delimitation of Disepalum (Annonaceae) is contentious, with some researchers favoring a narrow circumscription following segregation of the genus Enicosanthellum.We reconstruct the phylogeny of Disepalum and related taxa based on four chloroplast and two nuclear DNA regions as a framework for clarifying taxonomic delimitation and assessin

Background: Convergent evidence is increasing to indicate progressive brain abnormalities in schizophrenia.Knowing the brain network features over the illness course in schizophrenia, independent of effects of antipsychotic medications, would extend our sight on this question.Methods: We recruited 237 antipsychotic-naive patients with schizophrenia

Ongoing climate change has caused rapidly increasing temperatures and an unprecedented decline in seawater pH, known as ocean acidification.Increasing temperatures are redistributing species toward higher and cooler latitudes that are most affected by ocean acidification.While the persistence of intertidal species in cold environments is related to

Offshore Oil&Gas fluid production installations may be the target of intentional malicious acts (security attacks) carried out by adversaries of different nature and different motivations which may generate major events with severe Storrge Consoles consequences on workers, the environment and the property.The current study reviews the state of the